Benchmark indices opened lower on Wednesday, tracking weakness in Dow Jones futures that fell 2 percent indicating lower opening on Wall Street.
The 30-share BSE Sensex was down 127.47 points at 33,189.73 and the 50-share NSE Nifty fell 48.30 points to 10,201.
Tata Motors hit fresh 52-week low, falling half a percent.
Nifty Midcap index was down 113 points or 0.59 percent.
Union Bank, Canara Bank, PFC, Allahabad Bank and Karnataka Bank hit fresh 52-week lows.
Ashoka Buildcon, Sadbhav Infrastructure, Dilip Buildcon, TeamLease and Blue Star gained 1-2.5 percent.
